Glutathione-S-transferase M1, T1 and P1 polymorphisms, and breast cancer risk, in BRCA1/2 mutation carriers
نویسندگان
چکیده
منابع مشابه
Glutathione S-transferase M1, M3, P1, and T1 genetic polymorphisms and susceptibility to breast cancer.
This study was undertaken to examine if glutathione S-transferase (GST) M1, M3, P1, and T1 genotypes affected breast cancer risk in Finnish women. The study population consisted of 483 incident breast cancer cases and 482 healthy population controls. Genotyping analyses were performed by PCR-based methods, and odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by unconditional...
متن کاملGlutathione S-transferase P1 Genetic Polymorphisms and Breast Cancer Risk.
PURPOSE To evaluate the potential association between the GSTP1 genotype and the development of breast cancer, a hospital based case-control study was conducted in South Korea. MATERIALS AND METGODS: The study population consisted of 171 histologically confirmed incidents of breast cancer cases, and 171 age-matched controls with no present, or previous, history of cancer. A PCR method was used ...
متن کاملGlutathione S-transferases M1, T1, and P1 and breast cancer.
We examined associations for glutathione S-transferases M1 (GSTM1), T1 (GSTT1), and P1 (GSTP1) genotypes and breast cancer in the Carolina Breast Cancer Study, a population-based, case-control study in North Carolina. Odds ratios were close to the null value for each GST locus among African-American women (278 cases and 271 controls) and white women (410 cases and 392 controls), as well as pre-...
متن کاملAssociation of glutathione S-transferase T1, M1, and P1 polymorphisms in the breast cancer risk: a meta-analysis
BACKGROUND Several case-control studies investigating the relationship between genetic polymorphisms of glutathione S-transferase (GST) M1, GSTT1, and GSTP1 (rs1695) and the risk of breast cancer have reported contradictory results. We therefore performed a meta-analysis to clarify this issue. MATERIALS AND METHODS An updated meta-analysis using PubMed and Web of Knowledge databases for the e...
متن کاملAnalysis of glutathione S-transferase (M1, T1 and P1) gene polymorphisms in Iranian prostate cancer subjects
1 Genetic Research Group, Molecular and Bioinformatics Unit, Department of Biomedical Science, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 UPM Serdang, Selangor DE, Malaysia. 2 Department of Genetics, Faculty of Medicine, Tonekabon Islamic Azad University, Tonekabon, Mazandaran, Iran. 3 Department of Pathology, Faculty of Medicine and Health Sciences, University Pu...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2008
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6604394